PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Beryllium oxide | 1304-56-9 |
15.01
4.01
11.01
15.02
4.08
11.00
2.00
10.00
3.09
3.02
|
||||||||||
| Formula | Synonyms | |||||||||||
| BeO | BERYLLIA, BERYLLIUM & BERYLLIUM COMPOUNDS (AS BE), BERYLLIUM OXIDE, BROMELITE | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 25.01 | S crystals | 2578 | 3.01 |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.00042 | 0.025 | 0.10 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.00041 | 0.024 | 0.098 |
Technical Basis
A review of available sources identified the following: acute toxicity data for beryllium oxide and exposure limits (PEL-TWA, TLV-TWA, ERPGs) for beryllium (CASRN: 7440-41-7). Data sources were selected according to the hierarchy listed in Table 3.1. Although the analysts did evaluate the available acute toxicity data for beryllium oxide, these were sourced from a material safety data sheet, which is a less preferred source than ERPGs (Table 3.1). As such, the ERPGs for beryllium were selected as the TEEL-3 and TEEL-2 values. The TLV-TWA for beryllium was selected as the TEEL-1, and a compound adjustment factor was applied.
• TEEL-1 = MW-adjusted TLV-TWA (beryllium; CASRN 7440-41-7, 0.00005 mg/m3) x 3
• TEEL-2 = EPRG-2 (beryllium; CASRN 7440-41-7, 0.025 mg/m3)
• TEEL-3 = EPRG-3 (beryllium; CASRN 7440-41-7, 0.1 mg/m3)
This review generated TEEL values inconsistent with Rev. 29A. The Rev. 29A and current TEEL-3 and TEEL-2 sources, ERPGs, are consistent; however, the Rev. 29A TEELs applied a molecular-weight adjustment, while the current values are not adjusted, in accordance with Section 3.2.2. The Rev. 29A TEEL-1 was derived from the TEEL-2 (Table 3.5), while the current TEEL-1 basis is a molecular weight adjusted TLV-TWA exposure limit.
• TEEL-1 = MW-adjusted TLV-TWA (beryllium; CASRN 7440-41-7, 0.00005 mg/m3) x 3
• TEEL-2 = EPRG-2 (beryllium; CASRN 7440-41-7, 0.025 mg/m3)
• TEEL-3 = EPRG-3 (beryllium; CASRN 7440-41-7, 0.1 mg/m3)
This review generated TEEL values inconsistent with Rev. 29A. The Rev. 29A and current TEEL-3 and TEEL-2 sources, ERPGs, are consistent; however, the Rev. 29A TEELs applied a molecular-weight adjustment, while the current values are not adjusted, in accordance with Section 3.2.2. The Rev. 29A TEEL-1 was derived from the TEEL-2 (Table 3.5), while the current TEEL-1 basis is a molecular weight adjusted TLV-TWA exposure limit.
References
Acute toxicity data retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/14775
Beryllium exposure limits: https://www.osha.gov/chemicaldata/531
Beryllium TLV-TWA. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Beryllium
Beryllium ERPG: https://cameochemicals.noaa.gov/chemical/238