PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Trimethyltriheptylamine, 6,6',6''-; (Triisooctylamine) | 2757-28-0 |
15.02
|
||||||||||
| Formula | Synonyms | |||||||||||
| C24H51N | ||||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 353.76 |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 4.0 | 44 | 260 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.28 | 3.0 | 18 |
Technical Basis
A review of available sources identified acute toxicity data (LD50) for various species (rat, rabbit) and routes (dermal, oral). Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The most preferred species and route data, a rat oral LD50, was selected as the TEEL-3 basis. TEEL-2 and TEEL-1 values were derived according to Table 3.5.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = Rat oral LD50 (1321.92 mg/kg)
This review generated PAC values inconsistent with Rev. 29A. The Rev. 29A and current TEEL-3 are both based on rat oral LD50 toxicity data; however, this review used a more conservative dose. The Rev. 29A and current TEEL-2 and TEEL-1 methodology remains consistent, with differences in values due to the change of the TEEL-3 basis.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = Rat oral LD50 (1321.92 mg/kg)
This review generated PAC values inconsistent with Rev. 29A. The Rev. 29A and current TEEL-3 are both based on rat oral LD50 toxicity data; however, this review used a more conservative dose. The Rev. 29A and current TEEL-2 and TEEL-1 methodology remains consistent, with differences in values due to the change of the TEEL-3 basis.
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/Triisooctylamine.
Rat oral LD50. American Industrial Hygiene Association Journal., 23(95), 1962 [PMID:13914538]. Retrieved from (see Hazard Data > Hazard > Mortality Response Summary Value): https://comptox.epa.gov/dashboard/chemical/details/DTXSID60863017