PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Triphenyl phosphite | 101-02-0 |
6.00
15.01
11.01
14.02
4.08
4.05
8.00
7.00
11.00
4.07
|
||||||||||
| Formula | Synonyms | |||||||||||
| C18.H15.O3.P | TRIPHENYL PHOSPHITE, ADK STAB TPP, ADVANCE TPP, EFED, JP 360, MARK TPP, MELLITE 310, PHENYL PHOSPHITE ((C6H5O)3P), PHOSCLERE T 36, PHOSPHOROUS ACID, TRIPHENYL ESTER, SUMILIZER TPP-R, SUMILIZER TTP-R, TP 1, TP 1 (PLASTICIZER), TPP, TPP (PLASTICIZER), TPP-R, TRIPHENOXYPHOSPHINE, TRIS(PHENOXY)PHOSPHINE, WESTON TPP | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 310.3 | S | 1.184 |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 1.3 | 15 | 88 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.10 | 1.2 | 6.9 |
Technical Basis
A review of available sources identified acute toxicity data (LD50, LDLo, LC50) for several species and routes. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. Although there was a preferred inhalation data, the duration was not reported; therefore, it was not selected for TEEL development. Instead, two rat oral LD50 toxicity data were evaluated, and the most conservative dose was selected as the TEEL-3 basis. TEEL-2 and TEEL-1 values were derived according to Table 3.5.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = Rat oral LD50 (444 mg/kg)
This review generated PAC values inconsistent with Rev. 29A. The Rev. 29A and current TEEL-3 are both based on rat oral LD50 toxicity data; however, the current review used a more conservative dose. The Rev. 29A and current TEEL-2 and TEEL-1 methodology remains consistent, with differences in values due to the change of the TEEL-3 basis.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = Rat oral LD50 (444 mg/kg)
This review generated PAC values inconsistent with Rev. 29A. The Rev. 29A and current TEEL-3 are both based on rat oral LD50 toxicity data; however, the current review used a more conservative dose. The Rev. 29A and current TEEL-2 and TEEL-1 methodology remains consistent, with differences in values due to the change of the TEEL-3 basis.
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/Triphenyl-phosphite.
Rat oral LD50 (444 mg/kg). Gigiena i Sanitariya. For English translation, see HYSAAV., 46(12)(13), 1981. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Triphenyl-phosphite
Rat oral LD50 (1600 mg/kg). Lewis, R.J. Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold, 1996., p. 3315. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Triphenyl-phosphite
Rat LC50 (6.7 mg/L/no duration reported). Gabriel, K.L. 1980. Unpublished report no. 80-2010A entitled "Summary of results of acute toxicity studies", dated September 26, 1980 for Tenneco Chemicals Inc., Saddle Brook, NJ from Biosearch Inc., Philadelphia, PA. Retrieved from (see Hazard Data > Hazard > Mortality Response Summary Value): https://comptox.epa.gov/dashboard/chemical/details/DTXSID0026252