PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Tris(2-aminoethyl)amine | 4097-89-6 |
8.00
11.00
7.11
4.07
|
||||||||||
| Formula | Synonyms | |||||||||||
| C6.H18.N4 | ||||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 146.28 |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.74 | 8.1 | 49 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.12 | 1.4 | 8.2 |
Technical Basis
A review of available sources identified mouse and rat oral LD50 toxicity data. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The most preferred exposure of rat LD50 data was used as the starting point to estimate TEEL-3. TEEL-2 and TEEL-1 were calculated according to Table 3.5
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat oral LD50 (246 mg/kg)
This review generated TEEL-2 and TEEL-1 values that are more conservative and therefore inconsistent with those found in Rev 29A. While TEEL-3 remained the same due to using the same data source, the recommended TEEL-2 differs because the data source that was used in Rev. 29A, a rat oral TDLo, was not available and could not be referenced. This resulted in a different TEEL-1 value as well.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat oral LD50 (246 mg/kg)
This review generated TEEL-2 and TEEL-1 values that are more conservative and therefore inconsistent with those found in Rev 29A. While TEEL-3 remained the same due to using the same data source, the recommended TEEL-2 differs because the data source that was used in Rev. 29A, a rat oral TDLo, was not available and could not be referenced. This resulted in a different TEEL-1 value as well.
References
National Technical Information Service., OTS0537148 via PubChem; National Center for Biotechnology Information (2023). PubChem Compound Summary for CID 77731, Tris(2-aminoethyl)amine. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Tris_2-aminoethyl_amine.