PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Valeric acid; (n-Pentanoic acid) | 109-52-4 | 1760 |
5.10
11.00
7.01
8.00
14.02
14.01
11.01
4.01
|
|||||||||
| Formula | Synonyms | |||||||||||
| C5.H10.O2 | PENTANOIC ACID, 1-BUTANECARBOXYLIC ACID, BUTANECARBOXYLIC ACID, N-PENTANOIC ACID, N-VALERIC ACID, PROPYLACETIC ACID, VALERIANIC ACID, VALERIC ACID | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 102.15 | L | 186.4 | 0.196 | 25 | 0.940 @ 20°C | 16000 |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 15 | 24 | 140 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 3.6 | 5.7 | 34 |
Technical Basis
A review of available sources identified the following: an international occupational exposure limit TWA (OEL-TWA, Latvia), a mouse LC50 and several LD50 (oral, intravenous) toxicity data. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. Inhalation exposures were scaled to 60-minute equivalents using the ten Berge equation (Section 3.3.4). The mouse LC50 was selected as the TEEL-3 basis. TEEL-2 and TEEL-1 values were calculated according to Table 3.5.
• TEEL-1 = OEL-TWA (5 mg/ m3) x 3
• TEEL-2 = TEEL-3/6
• TEEL-3 = Mouse LC50 (4100 mg/m3/2H)
This review generated TEEL-3 and TEEL-2 values that are consistent with Rev. 29A. In Rev. 29A the TEEL-1 was derived according to Table 3.5, while the current review selected an OEL-TWA exposure limit as the basis.
• TEEL-1 = OEL-TWA (5 mg/ m3) x 3
• TEEL-2 = TEEL-3/6
• TEEL-3 = Mouse LC50 (4100 mg/m3/2H)
This review generated TEEL-3 and TEEL-2 values that are consistent with Rev. 29A. In Rev. 29A the TEEL-1 was derived according to Table 3.5, while the current review selected an OEL-TWA exposure limit as the basis.
References
https://cameochemicals.noaa.gov/chemical/1683
Mouse 2-hr LC50; Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure, Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982, (119), 1982. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Valeric-acid.
OEL-TWA: Search by CASRN at GESTIS International Limit Values: https://limitvalue.ifa.dguv.de/WebForm_gw2.aspx