PAC Database - Detailed Chemical Data

Chemical Identity
Chemical CAS# UN# Health Code Numbers
Bis(2-chlorethylthioethyl) ether; (2,2'-Di(3-chloroethylthio)diethyl ether) 63918-89-8
4.00
3.00
Formula Synonyms
C8H16Cl2OS2
Physical Properties
Mol Wt State MP (°C) BP (°C) VP (Hg) VP (°C) SG LEL (ppm)
263.26 L?
PAC Values
PAC Values (Original Units: mg/m3)
PAC-1 PAC-2 PAC-3
0.12 1.3 7.6
Converted PAC Values (ppm)
PAC-1 PAC-2 PAC-3
0.011 0.12 0.71
Technical Basis
A review of available data sources identified the following: human LCLo and mouse LC50 toxicity values. Human data is normally preferable, but lethal (50% kill) is a more preferred toxicity type than the lowest lethal concentration. Additionally, the mouse data is more current (2004) than the human data (1967). Therefore, the LC50 toxicity data was selected as the starting point for the TEEL-3. The ten Berge equation was used to time scale this concentration (Section 3.3.4). TEEL-2 and TEEL-1 values were derived according to Table 3.5.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Mouse 10-mintue LC50 (1650 mg/m3)
This review generated TEEL values consistent with those published in Rev. 29A
References
National Center for Biotechnology Information (2023). PubChem Compound Summary for CID 45452, O-Mustard. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/O-Mustard
Human LDLo (no exposure time listed): Science Journal., 3(4)(33), 1967; National Center for Biotechnology Information (2023). PubChem Compound Summary for CID 45452, O-Mustard. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/O-Mustard.
Mouse 10-min LC50: Lewis, R.J. Sr. (ed) Sax's Dangerous Properties of Industrial Materials. 11th Edition. Wiley-Interscience, Wiley & Sons, Inc. Hoboken, NJ. 2004., p. 1193; National Center for Biotechnology Information (2023). PubChem Annotation Record for O-Mustard, Source: Hazardous Substances Data Bank (HSDB). Retrieved from https://pubchem.ncbi.nlm.nih.gov/source/hsdb/8398
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PAC values marked with a subscript "A" correspond to 60-minute AEGL values.
PAC values marked with a subscript "E" correspond to ERPG values.
PAC values marked by * are >= 10% lower explosive limit (LEL) but < 50% LEL.
PAC values marked by ** are > 50% LEL but < 100% LEL.
PAC values marked by *** are >= LEL.