PAC Database - Detailed Chemical Data

Chemical Identity
Chemical CAS# UN# Health Code Numbers
Xylylene dichloride 28347-13-9
7.01
7.00
11.00
3.08
3.02
Formula Synonyms
C8H8Cl2 XYLYLENE DICHLORIDE, ALPHA,ALPHA^-DICHLOROXYLENE, BENZENE, 1,2-BIS(CHLOROMETHYL)-, BENZENE, 1,3-BIS(CHLOROMETHYL)-, BENZENE, 1,4-BIS(CHLOROMETHYL)-, BENZENE, BIS(CHLOROMETHYL)-, BIS(CHLOROMETHYL)BENZENE, DICHLOROXYLYLENE, M-XYLYLENE CHLORIDE, O-XYLYLENE CHLORIDE, P-XYLYLENE CHLORIDE, XYLENE, ALPHA,ALPHA'-DICHLORO-, XYLENE, ALPHA,ALPHA-DICHLORO-, XYLYLENE CHLORIDE
Physical Properties
Mol Wt State MP (°C) BP (°C) VP (Hg) VP (°C) SG LEL (ppm)
175.06 S 239 0.02 25 1.202
PAC Values
PAC Values (Original Units: mg/m3)
PAC-1 PAC-2 PAC-3
0.18 2.0 8.8
Converted PAC Values (ppm)
PAC-1 PAC-2 PAC-3
0.025 0.28 1.2
Technical Basis
A review of available sources identified rat and rabbit acute toxicity data (LC50, LD50, LDLo) for various routes, and a Level of Concern (LOC). Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The most preferred exposure type, a rat LC50, was selected as the TEEL-3 basis and was scaled to a 60-minute equivalent using the ten Berge equation (Section 3.3.4). The LOC was selected as the TEEL-2. The TEEL-1 value was derived according to Table 3.5.
• TEEL-1 = TEEL-2/11
• TEEL-2 = LOC (0.002 g/m3)
• TEEL-3 = Rat LC50 (200 mg/m3/4H)
This review generated TEEL values that are consistent with Rev. 29A*.
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/1_4-Bis_chloromethyl_benzene.
Rat LC50: Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 10(9), Pg. 36, 1966. Retrieved from https://comptox.epa.gov/dashboard/chemical/details/DTXSID10893081 (see Lethality Effect Level in Hazard Data section).
LOC: Retrieved from Appendix C (page C-10); https://www.epa.gov/sites/default/files/2015-09/documents/technical_guidance_for_hazard_analysis.pdf
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PAC values marked with a subscript "A" correspond to 60-minute AEGL values.
PAC values marked with a subscript "E" correspond to ERPG values.
PAC values marked by * are >= 10% lower explosive limit (LEL) but < 50% LEL.
PAC values marked by ** are > 50% LEL but < 100% LEL.
PAC values marked by *** are >= LEL.