PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Zinc acetate | 557-34-6 | 9153 |
15.01
11.01
4.06
4.10
4.07
3.09
3.02
3.10
3.07
5.00
|
|||||||||
| Formula | Synonyms | |||||||||||
| C4H6O4Zn | ZINC ACETATE, ZINC ACETATE DIHYDRATE, ZINC DIACETATE, ZINC(II) ACETATE, ACÉTATE DE ZINC (DOT FRENCH), ACETATO DE ZINC (DOT SPANISH), ACETIC ACID, ZINC SALT, DICARBOMETHOXYZINC, SILTEX CL 4 | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 183.47 | S | 237 | 1.735 |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 7.5 | 83 | 500 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 1.00 | 11 | 67 |
Technical Basis
A review of available sources identified mouse and rat LD50 acute toxicity data for oral and intraperitoneal exposures. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. Given species and route of administration preferences, the rat oral LD50 was selected as the TEEL-3 basis. TEEL-2 and TEEL-1 values were derived according to Table 3.5.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat oral LD50 (2510 mg/kg)
This review generated TEEL values inconsistent with Rev 29A. The Rev. 29A TEEL-3 basis was a mouse intraperitoneal LD50 that was identified in the current review; however, the recommended source is a more preferred species (rat > mouse) and route (oral > intraperitoneal) and resulted in a TEEL value that aligns closer to the health hazard rating of the substance (HHR=1). The TEEL-2 and TEEL-3 methodology remain consistent with the difference in values due to the change in the TEEL-3 basis.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat oral LD50 (2510 mg/kg)
This review generated TEEL values inconsistent with Rev 29A. The Rev. 29A TEEL-3 basis was a mouse intraperitoneal LD50 that was identified in the current review; however, the recommended source is a more preferred species (rat > mouse) and route (oral > intraperitoneal) and resulted in a TEEL value that aligns closer to the health hazard rating of the substance (HHR=1). The TEEL-2 and TEEL-3 methodology remain consistent with the difference in values due to the change in the TEEL-3 basis.
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/Zinc-Acetate
Rat oral LD50 (2510 mg/kg): Personal Communication from J.V. Marhold, VUOS, 539-18, Pardubice, Czechoslavakia, Mar. 29, 1977. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Zinc-Acetate
Mouse intraperitoneal LD50 (57 mg/kg): Toxicology and Applied Pharmacology., 49(41), 1979 [PMID:224529]. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Zinc-Acetate