PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Bis(2-ethylhexyl) hydrogen phosphate | 298-07-7 | 1902 |
14.01
4.01
11.01
14.02
4.10
4.07
4.11
10.00
|
|||||||||
| Formula | Synonyms | |||||||||||
| C16H35O4P | DI-(2-ETHYLHEXYL)PHOSPHORIC ACID, 1-HEXANOL, 2-ETHYL-, HYDROGEN PHOSPHATE, 2-ETHYL-1-HEXANOL HYDROGEN PHOSPHATE, ACIDE DI-(ÉTHYL-2 HEXYL) PHOSPHORIQUE (DOT FRENCH), ACIDO DI-(2-ETILHEXILO)FOSFÓRICO (DOT SPANISH), BIS(2-ETHYLHEXYL) HYDROGEN PHOSPHATE, BIS(2-ETHYLHEXYL) ORTHOPHOSPHATE, BIS(2-ETHYLHEXYL) PHOSPHATE, BIS-(2-ETHYLHEXYL)HYDROGEN PHOSPHATE, D 2EHPA, DEHPA, DI(2-ETHYLHEXYL) PHOSPHATE, DI(2-ETHYLHEXYL)ORTHOPHOSPHORIC ACID, DI(2-ETHYLHEXYL)PHOSPHORIC ACID, DI-(2-ETHYLHEXYL) PHOSPHATE, DI-(2-ETHYLHEXYL) PHOSPHORIC ACID, DI-2-ETHYLHEXYL HYDROGEN PHOSPHATE, DIOCTYL HYDROGEN PHOSPHATE, DIOCTYL ORTHOPHOSPHATE, DIOCTYL PHOSPHATE, DP 8R, HDEHP, HOSTAREX PA 216, HYDROGEN BIS(2-ETHYLHEXYL) PHOSPHATE, JP 508, LB 58, O,O-BIS(2-ETHYLHEXYL)PHOSPHORIC ACID, O,O-DI(2-ETHYLHEXYL)PHOSPHORIC ACID, ORTHOPHOSPHORIC ACID 2-ETHYLHEXYL ALCOHOL DIESTER, P 204, P 204 (ACID), PHOSPHORIC ACID DI(2-ETHYLHEXYL) ESTER | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 322.48 | L | 155.015 | 0.97525 |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 14 | 160 | 950 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 1.1 | 12 | 72 |
Technical Basis
A review of available sources identified rat acute toxicity data (LD50) for oral and intraperitoneal routes. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The preferred route toxicity data, a rat oral LD50, was selected as the TEEL-3 basis. The dose was reported in units of µL/kg; therefore, it was converted using its reported density of 0.975 g/cm3 (25°C). TEEL-2 and TEEL-1 values were derived according to Table 3.5.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat oral LD50 (4940 µL/kg converted to 4816.5 mg/kg with density = 0.975 g/cm3)
This review generated TEEL values inconsistent with Rev. 29A. The Rev. 29A TEEL-3 value was derived from the same source, a rat oral LD50 dose of 4940 uL/kg; however, the assumed density used in calculations was not the same, resulting in slight differences in the TEEL-3 values. The Rev. 29A and current TEEL-2 and TEEL-1 methodology remain consistent (Table 3.5), with differences due to the change in TEEL-3.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat oral LD50 (4940 µL/kg converted to 4816.5 mg/kg with density = 0.975 g/cm3)
This review generated TEEL values inconsistent with Rev. 29A. The Rev. 29A TEEL-3 value was derived from the same source, a rat oral LD50 dose of 4940 uL/kg; however, the assumed density used in calculations was not the same, resulting in slight differences in the TEEL-3 values. The Rev. 29A and current TEEL-2 and TEEL-1 methodology remain consistent (Table 3.5), with differences due to the change in TEEL-3.
References
Rat oral LD50: Union Carbide Data Sheet., 5/18/1972. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Bis_2-ethylhexyl_-hydrogen-phosphate.
Density: Lide, D.R. CRC Handbook of Chemistry and Physics 86TH Edition 2005-2006. CRC Press, Taylor & Francis, Boca Raton, FL 2005, p. 3-52: https://pubchem.ncbi.nlm.nih.gov/compound/Bis_2-ethylhexyl_-hydrogen-phosphate.
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/Bis_2-ethylhexyl_-hydrogen-phosphate