PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Butanediol, 1,4-; (1,4-Tetramethylene glycol) | 110-63-4 | 2346 |
15.01
4.01
15.02
4.08
7.01
8.00
7.00
11.00
4.09
4.06
|
|||||||||
| Formula | Synonyms | |||||||||||
| C4H10O2 | BUTANEDIONE, 1,4-BUTANEDIOL, 1,4-BUTYLENE GLYCOL, 1,4-DIHYDROXYBUTANE, 1,4-TETRAMETHYLENE GLYCOL, BUTANE-1,4-DIOL, BUTANEDIOL, BUTANEDIONE (DOT FRENCH), BUTANODIONA (DOT SPANISH), BUTYLENE GLYCOL, DABCO DBO, DIHYDROXYBUTANE, DIOL 14B, POLYCURE D, SUCOL B, TETRAMETHYLENE 1,4-DIOL, TETRAMETHYLENE GLYCOL | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 90.14 | L | 16 | 230 | 0.0105 | 25 | 3.1 | 19500 |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 9.8 | 110 | 640 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 2.7 | 30 | 170 |
Technical Basis
A review of available sources identified the following: LCLo (rat), LD50 (rat, mouse, rabbit, guinea pig), LDLo (man, woman). Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2 and evaluated using factors in Tables 3.2, 3.3, and 3.4. Although human acute toxicity is preferred, neither source identified a route appropriate for TEEL development. Instead, a rat LCLo, was selected as the TEEL-3 basis and scaled to 60-minute equivalent using the ten Berge equation (Section 3.3.4). The TEEL-2 and TEEL-1 values were calculated according to Table 3.5.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat LCLo (15 g/m3/4H)
This review generated a TEEL-3 value consistent with Rev. 29A. The TEEL-2 and TEEL-1 values are inconsistent with Rev. 29A; the Rev. 29A TEEL-2 basis was a mouse intraperitoneal TDLo, not found during the current review.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat LCLo (15 g/m3/4H)
This review generated a TEEL-3 value consistent with Rev. 29A. The TEEL-2 and TEEL-1 values are inconsistent with Rev. 29A; the Rev. 29A TEEL-2 basis was a mouse intraperitoneal TDLo, not found during the current review.
References
https://pubchem.ncbi.nlm.nih.gov/compound/1_4-Butanediol
Inhalation Toxicology., 3(379), 1991. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/1_4-Butanediol#section=Acute-Effects