A review of available sources identified the acute toxicity data (LCLo, LD50) for several species and routes. AEGLs for cadmium (Cd, CASRN: 7440-43-9) were considered to determine expected magnitude of TEELs for cadmium carbonate. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. Analysts selected the most preferred species and route toxicity data for cadmium carbonate, a rat LCLo as the TEEL-3 basis and it was scaled to a 60-minute equivalent using the ten Berge equation (Section 3.3.4). TEEL-2 and TEEL-1 values were derived according to Table 3.5.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat LCLo (203 mg/m3/2H)
This review generated TEEL values inconsistent with Rev. 29A. The Rev. 29A TEELs were molecular weight adjusted cadmium AEGLs; per Section 3.2.2, AEGLs may not be weight adjusted. Instead, analysts selected available acute toxicity data for cadmium carbonate as the TEEL-3 basis and derived TEEL-2 and TEEL-1 values according to Table 3.5.