PAC Database - Detailed Chemical Data

Chemical Identity
Chemical CAS# UN# Health Code Numbers
Cadmium sulfate, hydrate 7790-84-3
2.00
5.10
4.07
4.09
11.00
11.01




Formula Synonyms
CdH16O12S
Physical Properties
Mol Wt State MP (°C) BP (°C) VP (Hg) VP (°C) SG LEL (ppm)
256.51 S crystals 3.79 @ 20°C
PAC Values
PAC Values (Original Units: mg/m3)
PAC-1 PAC-2 PAC-3
0.91 10 60
Converted PAC Values (ppm)
PAC-1 PAC-2 PAC-3
0.087 0.95 5.7
Technical Basis
A review of available sources did not identify exposure limits or acute toxicity data for cadmium sulfate hydrate. Instead, analysts evaluated available sources for cadmium nitrate (CdSO4, CASRN: 10124-36-4) and cadmium (CASRN: 7440-43-9). AEGLs for cadmium (CASRN: 7440-43-9) were considered to determine an approximate magnitude of TEELs for cadmium sulfate hydrate. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4.  Analysts selected the most preferred route and species toxicity data, a rat oral LD50, as the TEEL-3 basis and a molecular weight adjustment was applied (Section 3.4.3.2). TEEL-2 and TEEL-1 values were derived according to Table 3.5.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3= MW-adjusted rat oral LD50 (cadmium sulfate, CASRN: 10124-36-4, 280 mg/kg)
This review generated TEEL values that are inconsistent with Rev. 29A. The Rev. 29A TEELs were molecular weight adjusted cadmium AEGLs; per Section 3.2.2, AEGLs may not be weight adjusted. Instead, analysts selected available acute toxicity data for cadmium sulfate as the TEEL-3 basis and applied a molecular weight adjustment (Section 3.4.3.2); TEEL-2 and TEEL-1 values according to Table 3.5.
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/Cadmium-sulfate-hydrate
Cadmium sulfate information: https://pubchem.ncbi.nlm.nih.gov/compound/Cadmium-Sulfate
Rat LD50 for cadmium sulfate (CASRN: 10124-36-4). Aktual'nye Problemy Gigieny Truda. Current Problems of Labor Hygiene, Tarasenko, N.Y., ed. Moscow, Pervyi Moskovskii Meditsinskii Inst., 1978, -(14), 1978. Retreived from: https://pubchem.ncbi.nlm.nih.gov/compound/Cadmium-Sulfate
Cadmium AEGLs: https://www.epa.gov/aegl/cadmium-results-aegl-program
Cadmium IDLH: https://www.cdc.gov/niosh/idlh/7440439.html
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