PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Alkyl dimethylbenzyl ammonium chloride; (Benzalkonium chloride) | 8001-54-5 |
4.07
14.01
11.01
14.02
4.08
7.01
8.00
11.00
7.10
4.09
|
||||||||||
| Formula | Synonyms | |||||||||||
| [Unspecified] | ||||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 0 | S | 34.37 | 0.9884 @ 20°C |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.72 | 7.9 | 48 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0 | 0 | 0 |
Technical Basis
A review of available sources identified the following rat oral and intraperitoneal toxicity studies. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. Analyst selected the lowest dose rat oral LD50 as the TEEL-3 basis. TEEL-2 and TEEL-1 values were derived according to Table 3.5.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat oral LD50 (240 mg/kg)
This review generated TEEL values inconsistent with Rev. 29A. TEEL-3 basis was rat oral LD50 for both Rev. 29A and the new recommendation. The study used for the Rev. 29A evaluation was not found during this review; instead, analysts used the available rat oral LD50, a lower dose. The Rev. 29A and current TEEL-2 and TEEL-1 methodology remain consistent, with differences in values due to the change of the TEEL-3 basis.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat oral LD50 (240 mg/kg)
This review generated TEEL values inconsistent with Rev. 29A. TEEL-3 basis was rat oral LD50 for both Rev. 29A and the new recommendation. The study used for the Rev. 29A evaluation was not found during this review; instead, analysts used the available rat oral LD50, a lower dose. The Rev. 29A and current TEEL-2 and TEEL-1 methodology remain consistent, with differences in values due to the change of the TEEL-3 basis.
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/Benzododecinium-chloride
Rat LD50. Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 219, 1970. See ‘Mortality Response Summary’ from dropdown menu from: https://comptox.epa.gov/dashboard/chemical/hazard/DTXSID9034317