PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Carbaryl | 63-25-2 | 2757 |
6.00
15.01
4.01
14.02
4.08
4.05
7.01
8.00
7.00
4.06
|
|||||||||
| Formula | Synonyms | |||||||||||
| C12H11NO2 | CARBARYL, 1-NAPHTHALENOL, METHYLCARBAMATE, 1-NAPHTHOL N-METHYLCARBAMATE, 1-NAPHTHYL METHYLCARBAMATE, 1-NAPHTHYL N-METHYL-CARBAMATE, 1-NAPHTHYL N-METHYLCARBAMATE, AGREX S, ALPHA-NAPHTHALENYL METHYLCARBAMATE, ALPHA-NAPHTHYL METHYLCARBAMATE, ALPHA-NAPHTHYL N-METHYL-CARBAMATE, ARILAT, ARILATE, ARYLAM, ATOXAN, CAPROLIN, CARBAMIC ACID, METHYL-, 1-NAPHTHYL ESTER, CARBARIL, CARBARILO (DOT SPANISH), CARBARYL (DOT FRENCH), CARBATOX, CARBATOX 60, CARBATOX 75, CARBAVUR, CARBOMATE, CARVIN, COMPOUND 7744, DENAPON, DICARBAM, DICARBAM 50, DYNA-CARBYL, ENT 23969, EXPERIMENTAL INSECTICIDE 7744, GERMAIN^S, HEXAVIN, KARBATOX, KARBATOX 75, KARBATOX ZAWIESINOWY, KARBOSEP, LAIVIN, LAIVIN 85, MENAPHTAM, MONSUR, MUGAN, MURVIN, NAC, NAC (INSECTICIDE), NMC 50, OLTITOX, PANAM, POMEX, PROSEVOR 85, RAVYON, SEFFEIN, SEVIMOL, SEVIN, SEVIN 4, SEVIN 4L, SEVIN 50WP, SEVIN 75, SEVIN S 50, SEVIN®, SEWIN, SUVAMIL, SUVAMIL 50, SUVAVIL L, THINSEC, UNION CARBIDE 7744, VETOX, VIOXAN, XLR-PLUS | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 201.22 | S | 145 | 25 | 1.228 |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 5.0 | 300 | 600 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.61 | 36 | 73 |
Technical Basis
A review of available sources identified exposure limits (IDLH, STELs, TWAs) and acute toxicity data (LD50, LDLo, TDLo) for several species and routes. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. Analysts evaluated human toxicity data (LDLo) to determine an appropriate magnitude for TEEL-3 values. Considering this, analysts selected the 1990 IDLH as the TEEL-3. The human male oral TDLo was selected as the TEEL-2 basis. The OEL-STEL (15-minute, Romania) was selected as the TEEL-1.
• PAC-1 = TEEL-1 = OEL-STEL (5 mg/m3)
• PAC-2 = TEEL-2 = Human male oral TDLo (500 mg/kg)
• PAC-3 = TEEL-3 = IDLH (1990; 600 mg/m3)
This review generated PAC-2 and PAC-1 values inconsistent with Rev. 29A. The Rev. 29A TEEL-2 was derived from the TEEL-3, while the current TEEL-2 basis is a human toxicity data (TDLo). The Rev. 29A TEEL-1 basis was a TLV-TWA, while the current TEEL-1 is a 15-minute STEL (Romania), a more preferred source (See note in Table 3.5). The Rev. 29A and current PAC-3 values, source, and methodology are consistent.
• PAC-1 = TEEL-1 = OEL-STEL (5 mg/m3)
• PAC-2 = TEEL-2 = Human male oral TDLo (500 mg/kg)
• PAC-3 = TEEL-3 = IDLH (1990; 600 mg/m3)
This review generated PAC-2 and PAC-1 values inconsistent with Rev. 29A. The Rev. 29A TEEL-2 was derived from the TEEL-3, while the current TEEL-2 basis is a human toxicity data (TDLo). The Rev. 29A TEEL-1 basis was a TLV-TWA, while the current TEEL-1 is a 15-minute STEL (Romania), a more preferred source (See note in Table 3.5). The Rev. 29A and current PAC-3 values, source, and methodology are consistent.
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/Carbaryl
OEL (TWAs, STELs): https://ilv.ifa.dguv.de/limitvalues/10023
IDLH: https://www.cdc.gov/niosh/idlh/63252.html
Human male (TDLo, 500 mg/kg). Neurology., 37(1229), 1987 [PMID:3037439]. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Carbaryl
Female oral LDLo (5000 mg/kg). Human & Experimental Toxicology., 11(373), 1992 [PMID:1358154]. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Carbaryl