PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Carbophenothion; (Trithion) | 786-19-6 |
6.00
15.01
4.01
4.08
4.05
7.01
7.00
11.00
4.07
3.08
|
||||||||||
| Formula | Synonyms | |||||||||||
| C11H16ClO2PS3 | CARBOPHENOTHION, ACARITHION, AKARITHION, CARBOFENOTHION, CARBOFENOTION, CARBOFENTHION, DAGADIP, ENDYL, ENT 23,708, ETHYL CARBOPHENOTHION, GARRATHION, HEXATHION, LETHOX, NEPHOCARP, O,O-DIETHYL S-(P-CHLOROPHENYLTHIO)METHYL PHOSPHORODITHIOATE, O,O-DIETHYL S-P-CHLOROPHENYLTHIOMETHYL DITHIOPHOSPHATE, OLEOAKARITHION, PHOSPHORODITHIOIC ACID, S-(((4-CHLOROPHENYL)THIO)METHYL) O,O, PHOSPHORODITHIOIC ACID, S-(((P-CHLOROPHENYL)THIO)METHYL) O,O, PHOSPHORODITHIOIC ACID, S-[[(P-CHLOROPHENYL)THIO]METHYL] O,O, R 1303, R 1303 (PESTICIDE), R-1303, S-(((P-CHLOROPHENYL)THIO)METHYL) O,O-DIETHYL PHOSPHORODITHIO, S-(4-CHLOROPHENYLTHIOMETHYL) DIETHYL PHOSPHOROTHIOLOTHIONATE, S-[[(P-CHLOROPHENYL)THIO]METHYL] O,O-DIETHYL PHOSPHORODITHIO, STAUFFER R 1303, STAUFFER R-1,303, TRITHION, TRITHION MITICIDE | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 342.87 | L | 0.0000003 | 20 | 1.29 @ 20°C |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.020 | 0.22 | 1.3 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.0014 | 0.016 | 0.093 |
Technical Basis
A review of available sources identified a LOC and several LD50 toxicity for various species and routes. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The most conservative and recent rat oral LD50 was selected as the TEEL-3 basis. The LOC was evaluated as the TEEL-2; however, available acute toxicity data generated TEEL-3 values (1.3 to 4.0 mg/m3) that indicate the LOC is not sufficiently conservative. As such, TEEL-1 and TEEL-2 values were derived according to Table 3.5.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = Rat oral LD50 (6800 ug/kg => 6.8 mg/kg)
This review generated PAC values inconsistent with Rev. 29A. The Rev. 29A TEEL-3 basis was a mouse oral LD50, while the current basis is an oral LD50 of a more preferred species (rat > mouse, Section 3.3.2). The Rev. 29A TEEL-2 was the LOC; however, the current TEEL-2 value was derived from the TEEL-3 (Table 3.5). The Rev. 29A and current TEEL-1 methodology are consistent, with the difference in values due to the change of the TEEL-2 basis.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = Rat oral LD50 (6800 ug/kg => 6.8 mg/kg)
This review generated PAC values inconsistent with Rev. 29A. The Rev. 29A TEEL-3 basis was a mouse oral LD50, while the current basis is an oral LD50 of a more preferred species (rat > mouse, Section 3.3.2). The Rev. 29A TEEL-2 was the LOC; however, the current TEEL-2 value was derived from the TEEL-3 (Table 3.5). The Rev. 29A and current TEEL-1 methodology are consistent, with the difference in values due to the change of the TEEL-2 basis.
References
Chemical information. https://pubchem.ncbi.nlm.nih.gov/compound/Carbophenothion.
Rat oral LD50: Farm Chemicals Handbook., -(C315), 1991. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Carbophenothion
LOC: Appendix C; page C-3: https://www.epa.gov/sites/default/files/2015-09/documents/technical_guidance_for_hazard_analysis.pdf