PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Chloro-2,4-dinitrobenzene, 1- | 97-00-7 | 1577 |
13.00
14.01
4.01
14.02
4.05
7.01
7.00
11.00
4.07
3.05
|
|||||||||
| Formula | Synonyms | |||||||||||
| C6.H3.Cl.N2.O4 | DINITROCHLOROBENZENE, 1,3-DINITRO-4-CHLOROBENZENE, 1-CHLORO-2,4-DINITROBENZENE, 2,4-DINITRO-1-CHLOROBENZENE, 2,4-DINITROCHLOROBENZENE, 2,4-DINITROPHENYL CHLORIDE, 4-CHLORO-1,3-DINITROBENZENE, 6-CHLORO-1,3-DINITROBENZENE, CDNB, CHLORODINITROBENZENE, DINITROCHLOROBENZÈNES (DOT FRENCH), DINITROCLOROBENCENO (DOT SPANISH), DNCB | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 202.56 | S | 315 | 1.68 | 20000 |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 1.0 | 21 | 130 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.12 | 2.5 | 16 |
Technical Basis
A review of available sources identified rat LD50 toxicity data for oral and intraperitoneal routes, and an OEL-STEL (Romania). Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The data of the most preferred route, a rat oral LD50, was selected as the TEEL-3 basis. The OEL-STEL (Romania) was selected as the TEEL-1. The TEEL-2 value was derived according to Table 3.5.
• TEEL-1 = OEL-STEL (Romania) (1 mg/m3)
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat oral LD50 (640 mg/kg)
This review generated TEEL values inconsistent with Rev. 29A. The Rev. 29A TEEL-3 basis was also based on rat oral LD50 toxicity data, however the current recommendation is based on a slightly more conservative dose than that used in the Rev. 29A. The TEEL-2 basis in Rev. 29A was a rat oral TDLo that was not found in this review, and instead the TEEL-2 was derived from the TEEL-3. For the TEEL-1, an OEL-STEL (Romania) was selected and was not derived according to Table 3.5 as in Rev. 29A.
• TEEL-1 = OEL-STEL (Romania) (1 mg/m3)
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat oral LD50 (640 mg/kg)
This review generated TEEL values inconsistent with Rev. 29A. The Rev. 29A TEEL-3 basis was also based on rat oral LD50 toxicity data, however the current recommendation is based on a slightly more conservative dose than that used in the Rev. 29A. The TEEL-2 basis in Rev. 29A was a rat oral TDLo that was not found in this review, and instead the TEEL-2 was derived from the TEEL-3. For the TEEL-1, an OEL-STEL (Romania) was selected and was not derived according to Table 3.5 as in Rev. 29A.
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/Dinitrochlorobenzene.
OEL-STEL (Romania): https://ilv.ifa.dguv.de/limitvalues/12273
Rat oral LD50: Archiv fuer Gewerbepathologie und Gewerbehygiene., 17(217), 1959 [PMID:13854998] Found in: https://pubchem.ncbi.nlm.nih.gov/compound/Dinitrochlorobenzene.