PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Chloroacetic acid, sodium salt | 3926-62-3 | 2659 |
15.01
4.01
11.01
15.02
7.01
7.00
11.00
4.07
3.02
3.10
|
|||||||||
| Formula | Synonyms | |||||||||||
| C2H2ClNaO2 | SODIUM CHLOROACETATE, CHLORACÉTATE DE SODIUM (DOT FRENCH), CHLOROACETIC ACID SODIUM SALT, CLOROACETATO DE SODIO (DOT SPANISH), MONOCHLOROACETIC ACID SODIUM SALT, SMA, SMA (HERBICIDE), SODIUM 2-CHLOROACETATE, SODIUM ALPHA-CHLOROACETATE, SODIUM CHLOROETHANOATE, SODIUM MONOCHLOROACETATE | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 116.48 | S crystals |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 4.0 | 44 | 260 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.84 | 9.2 | 55 |
Technical Basis
A review of available sources identified exposure limits (OEL STELs and TWAs, WEEL-TWA), and acute toxicity data (LC50, LD50) for several species and routes. Reported GHS health hazard ratings (H318, H330, Category 1; H315 and H319, Category 2; H301, H311, H331, H335, Category 3) indicate a mid-level health hazard, approximately equivalent to an HHR=2 (TEEL-3 = 790 mg/m3). Analysts evaluated the toxicity data; of these, the resultant TEEL-3 values ranged from 6-11 mg/m3. These values are significantly more conservative that the GHS health hazards indicate and are the same order of magnitude of available exposure limits. Considering this, these sources were not selected for TEEL development. There were no available sources to derive the TEEL-2. The MAK-STEL (Germany DFG, inhalable fraction, 15-minutes). TEEL-2 and TEEL-3 values were derived according to Table 3.5.
• PAC-1 = TEEL-1 = MAK-STEL (4 mg/m3)
• PAC-2 = TEEL-2 = TEEL-1 x 11
• PAC-3 = TEEL-3 = TEEL-2 x 6
This review generated PAC values that are inconsistent with Rev. 29A. The Rev. 29A TEEL-1 basis was a WEEL-TWA, while the current TEEL-1 is a MAK-STEL (Table 3.1). The Rev. 29A and current TEEL-2 and TEEL-3 use the same methodology, with differences due to the change in TEEL-1.
• PAC-1 = TEEL-1 = MAK-STEL (4 mg/m3)
• PAC-2 = TEEL-2 = TEEL-1 x 11
• PAC-3 = TEEL-3 = TEEL-2 x 6
This review generated PAC values that are inconsistent with Rev. 29A. The Rev. 29A TEEL-1 basis was a WEEL-TWA, while the current TEEL-1 is a MAK-STEL (Table 3.1). The Rev. 29A and current TEEL-2 and TEEL-3 use the same methodology, with differences due to the change in TEEL-1.
References
Chemical information and acute toxicity data retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Chloroacetic-acid
MAK-STEL: https://ilv.ifa.dguv.de/limitvalues/11576
WEEL-TWA: https://tera.org/OARS/