PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Copper sulfate; (Copper(II) sulfate) | 7758-98-7 | 9109 |
14.01
11.01
14.02
4.05
7.01
8.00
7.00
4.08
4.01
11.00
|
|||||||||
| Formula | Synonyms | |||||||||||
| CuO4S | CUPRIC SULFATE, BLUE COPPER, BLUE STONE, BLUE VITRIOL, COPPER MONOSULFATE, COPPER SULFATE, COPPER SULFATE (1:1), COPPER SULFATE (CUSO4), COPPER SULFATE PENTAHYDRATE, COPPER(2+) SULFATE, COPPER(2+) SULFATE (1:1), COPPER(II) SULFATE, CUPRIC SULFATE ANHYDROUS, CUPRIC SULPHATE, HYLINEC, INCRACIDE 10A, INCRACIDE E 51, MAC 570, MONOCOPPER SULFATE, ROMAN VITRIOL, SULFATE CUIVRIQUE (DOT FRENCH), SULFATE OF COPPER, SULFATO CÚPRICO (DOT SPANISH), SULFURIC ACID, COPPER(2+) SALT (1:1) | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 159.6 | S | 3.6 |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 7.5 | 9.9 | 59 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 1.1 | 1.5 | 9.0 |
Technical Basis
A compound adjustment factor (Section 3.2.2) was calculated and used to develop TEEL-1 from the copper TLV-TWA. Multiple toxicity doses were identified for TEEL-3 development. Of these, the rat oral LD50 data (300 mg/kg) was selected, considering route/species preferability and dose repeatability across recent credible sources (Section 3.3).
• WHO; Environ Health Criteria 200: Copper p.101 (1998)
• Antifungal Compounds, Siegel, M.R., and H.D. Sisler, eds., 2 vols., New York, Marcel Dekker 1977, 1(507), 1977
Applicable data was not found for TEEL-2, therefore a value was derived from the TEEL-3, as indicated in Table 3.5.
• TEEL-1 = MW-adjusted copper (CASRN: 7440-50-8) TLV-TWA x 3
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat oral LD50 (300 mg/kg)
This recommendation is consistent with Rev. 29A.
• WHO; Environ Health Criteria 200: Copper p.101 (1998)
• Antifungal Compounds, Siegel, M.R., and H.D. Sisler, eds., 2 vols., New York, Marcel Dekker 1977, 1(507), 1977
Applicable data was not found for TEEL-2, therefore a value was derived from the TEEL-3, as indicated in Table 3.5.
• TEEL-1 = MW-adjusted copper (CASRN: 7440-50-8) TLV-TWA x 3
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat oral LD50 (300 mg/kg)
This recommendation is consistent with Rev. 29A.
References
https://cameochemicals.noaa.gov/chemical/3025
Prioritization of the Oral (Ingestive) Hazard of Industrial Chemicals; https://apps.dtic.mil/sti/pdfs/ADA552625.pdf
Rat oral LD50: WHO; Environ Health Criteria 200: Copper p.101 (1998); via PubChem; National Center for Biotechnology Information (2023). PubChem Compound Summary for CID 24462, Cupric Sulfate. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Cupric-Sulfate
American Conference of Governmental Industrial Hygienists TLVs and BEIs; via PubChem; National Center for Biotechnology Information (2023). PubChem Compound Summary for CID 24462, Cupric Sulfate. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Cupric-Sulfate