PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Crystal violet; (Aniline violet) | 548-62-9 |
5.10
11.00
4.07
7.01
3.07
4.01
10.00
7.11
7.10
3.06
|
||||||||||
| Formula | Synonyms | |||||||||||
| C25.H30.N3.Cl | HEXAMETHYL-P-ROSANILINE CHLORIDE, ((4-BIS(P-(DIMETHYLAMINO)PHENYL)METHYLENE)-2,5-CYCLOHEXADIEN, 12416 VIOLET, ADERGON, AIZEN CRYSTAL VIOLET, AIZEN CRYSTAL VIOLET EXTRA PURE, ANILINE VIOLET, ANILINE VIOLET PYOKTANINE, ATMONIL, AVERMIN, AXURIS, BADIL, BASIC VIOLET 3, BASIC VIOLET BN, BISMUTH VIOLET, BRILLIANT VIOLET 58, C.I. 42555, C.I. BASIC VIOLET 3, C.I. 42555, C.I. BASIC VIOLET 3, CALCOZINE VIOLET 6BN, CALCOZINE VIOLET C, CRYSTAL VIOLET, CRYSTAL VIOLET 10B, CRYSTAL VIOLET 5BO, CRYSTAL VIOLET 6B, CRYSTAL VIOLET 6BO, CRYSTAL VIOLET AO, CRYSTAL VIOLET AON, CRYSTAL VIOLET BASE, CRYSTAL VIOLET BP, CRYSTAL VIOLET BPC, CRYSTAL VIOLET CHLORIDE, CRYSTAL VIOLET EXTRA PURE, CRYSTAL VIOLET EXTRA PURE APN, CRYSTAL VIOLET EXTRA PURE APNX, CRYSTAL VIOLET FN, CRYSTAL VIOLET HL 2, CRYSTAL VIOLET HL2, CRYSTAL VIOLET O, CRYSTAL VIOLET PURE DSC, CRYSTAL VIOLET PURE DSC BRILLIANT, CRYSTAL VIOLET SS, CRYSTAL VIOLET TECHNICAL, CRYSTAL VIOLET USP, GENETIAN VIOLET, GENTERSAL, GENTIAN VIOLET, GENTIAN VIOLET B, GENTIAVERM, GENTICID, GENTIOLETTEN, HECTO VIOLET R, HECTOGRAPH VIOLET SR, HEXAMETHYL P-ROSANILINE HYDROCHLORIDE, HEXAMETHYL VIOLET, HEXAMETHYL-P-ROSANILINE HYDROCHLORIDE, HEXAMETHYLPARAOSANILINE CHLORIDE, HEXAMETHYLPARAROSANILINE CHLORIDE, HIDACO BRILLIANT CRYSTAL VIOLET, HIDACO CRYSTAL VIOLET, MEROXYL-WANDER, MEROXYLAN-WANDER, MEROXYLANWANDER, METHYL VIOLET, METHYL VIOLET 10B, METHYL VIOLET 10BD, METHYL VIOLET 10BK, METHYL VIOLET 10BN, METHYL VIOLET 10BNS, METHYL VIOLET 10BO, METHYL VIOLET 5BNO, METHYL VIOLET 5BO, METHYL VIOLET 6B, METHYL VIOLET 6B (BIOLOGICAL STAIN), METHYLAMMONIUM CHLORIDE, METHYLROSANILINE CHLORIDE, MITSUI CRYSTAL VIOLET, NCI-C55969, OXIURAN, OXYCOLOR, OXYOZYL, PAPER BLUE R, PARAROSANILINE, N,N,N^,N',N'',N''-HEXAMETHYL-, CHLORIDE, PLASTORESIN VIOLET 5BO, PYOKTANIN, SANYO FANAL VIOLET R, VERMICID, VIANIN, VIOCID, VIOLET 5BO, VIOLET 6BN, VIOLET CP, VIOLET XXIII | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 408.03 | S | 215 |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 1.3 | 14 | 83 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.078 | 0.84 | 5.0 |
Technical Basis
A review of available sources identified acute toxicity data (LD50, LDLo) for numerous species and routes. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The most preferred route and species, a rat oral LD50, was selected as the TEEL-3 basis. TEEL-2 and TEEL-1 values were derived according to Table 3.5.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat oral LD50 (420 mg/kg)
This review generated TEEL-1 and TEEL-2 values that are inconsistent with Rev. 29A. The TEEL-3 values and source are consistent with Rev. 29A. The Rev. 29A TEEL-2 basis was a rat TDLo that was not found during the current review; instead, the TEEL-2 was derived from the TEEL-3. The Rev. 29A and current TEEL-1 were derived using the same methodology (Table 3.5), with the difference due to the change in TEEL-2.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat oral LD50 (420 mg/kg)
This review generated TEEL-1 and TEEL-2 values that are inconsistent with Rev. 29A. The TEEL-3 values and source are consistent with Rev. 29A. The Rev. 29A TEEL-2 basis was a rat TDLo that was not found during the current review; instead, the TEEL-2 was derived from the TEEL-3. The Rev. 29A and current TEEL-1 were derived using the same methodology (Table 3.5), with the difference due to the change in TEEL-2.
References
Rat LD50; Arzneimittel-Forschung. Drug Research., 1(5), 1951 [PMID:14838774]. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Gentian-Violet