PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cupric acetate, anhydrous; (Copper acetate) | 142-71-2 | 9106 |
14.01
11.01
15.02
4.08
4.05
7.01
8.00
7.00
4.06
4.07
|
|||||||||
| Formula | Synonyms | |||||||||||
| C4H6CuO4 | CUPRIC ACETATE, ACÉTATE CUIVRIQUE (DOT FRENCH), ACETATO CÚPRICO (DOT SPANISH), ACETIC ACID CUPRIC SALT, ACETIC ACID, CUPRIC SALT, COPPER ACETATE, COPPER ACETATE (CU(C2H3O2)2), COPPER ACETATE (CU(MECO2)2), COPPER ACETATE (CU(OAC)2), COPPER DIACETATE, COPPER(2+) ACETATE, COPPER(2+) DIACETATE, COPPER(II) ACETATE, CRYSTALLIZED VERDIGRIS, CRYSTALS OF VENUS, CUPRIC ACETATE MONOHYDRATE, CUPRIC DIACETATE, NEUTRAL VERDIGRIS, VENUS COPPER | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 181.64 | S |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 8.6 | 17 | 99 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 1.2 | 2.3 | 13 |
Technical Basis
A review of available sources identified acute toxicity data (LD50) for several species and routes. In addition, analysts evaluated exposure limits (TWAs) for copper (CASRN: 7440-50-8) for TEEL development (Section 3.4.6). Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The most preferred species and route toxicity data, a rat oral LD50, was selected as the TEEL-3 basis. TEEL-2 was derived according to Table 3.5. The TLV-TWA for copper was selected as the TEEL-1 basis and a compound adjustment factor was applied (Section 3.2.2).
• PAC-1 = TEEL-1 = MW-adjusted TLV-TWA (copper, CASRN: 7440-50-8, 1 mg/m3) x 3
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = Rat oral LD50 (501 mg/kg)
This review generated a PAC-1 value consistent with Rev. 29A and inconsistent PAC-2 and PAC-3 values. The Rev. 29A TEEL-3 basis was a rat oral LD50; the current review identified a rat oral LD50 with a lower dose. Rev. 29A and current TEEL-2 use the same methodology, with differences due to the change of the TEEL-3. The Rev. 29A and current TEEL-1 source, and methodology are consistent.
• PAC-1 = TEEL-1 = MW-adjusted TLV-TWA (copper, CASRN: 7440-50-8, 1 mg/m3) x 3
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = Rat oral LD50 (501 mg/kg)
This review generated a PAC-1 value consistent with Rev. 29A and inconsistent PAC-2 and PAC-3 values. The Rev. 29A TEEL-3 basis was a rat oral LD50; the current review identified a rat oral LD50 with a lower dose. Rev. 29A and current TEEL-2 use the same methodology, with differences due to the change of the TEEL-3. The Rev. 29A and current TEEL-1 source, and methodology are consistent.
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/Cupric-acetate
Rat LD50. Indian Journal of Pharmacology., 23(153), 1991. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Cupric-acetate
Exposure limits, copper (CASRN: 7440-50-8) retrieved from: https://www.osha.gov/chemicaldata/1030