PAC Database - Detailed Chemical Data

Chemical Identity
Chemical CAS# UN# Health Code Numbers
Cyanophos 2636-26-2
6.00
15.01
4.01
11.01
4.08
4.05
7.01
7.00
11.00
4.07
Formula Synonyms
C9.H10.N.O3.P.S CYANOPHOS, BAY 34727, BAYER 34727, CIAFOS, CYANOFOS, CYANOX, CYAP, ENT 25,675, O,O-DIMETHYL O-(4-CYANOPHENYL) PHOSPHOROTHIOATE, O,O-DIMETHYL O-(P-CYANOPHENYL) PHOSPHOROTHIOATE, O,O-DIMETHYL O-4-CYANOPHENYL PHOSPHOROTHIOATE, O,O-DIMETHYL O-4-CYANOPHENYL THIOPHOSPHATE, O,O-DIMETHYL-O-P-CYANOPHENYL PHOSPHOROTHIOATE, O-P-CYANOPHENYL O,O-DIMETHYL PHOSPHOROTHIOATE, PHOSPHOROTHIOIC ACID O-(4-CYANOPHENYL) O,O-DIMETHYL ESTER, PHOSPHOROTHIOIC ACID, O,O-DIMETHYL ESTER, O-ESTER WITH P-HYD, PHOSPHOROTHIOIC ACID, O-P-CYANOPHENYL O,O-DIMETHYL ESTER, S 4084, SUMITOMO S 4084, SUNITOMO S 4084
Physical Properties
Mol Wt State MP (°C) BP (°C) VP (Hg) VP (°C) SG LEL (ppm)
243.23 L 1.255-1.265
PAC Values
PAC Values (Original Units: mg/m3)
PAC-1 PAC-2 PAC-3
2.3 25 43
Converted PAC Values (ppm)
PAC-1 PAC-2 PAC-3
0.23 2.5 4.3
Technical Basis
A review of available sources identified rat and mouse LD50 toxicity data for various routes, and an LOC. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The most preferred species and route data, a rat oral LD50, was selected as the TEEL-3 basis. The LOC was selected as the TEEL-2. The TEEL-1 value was derived according to Table 3.5.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = LOC (0.025 g/m3)
• PAC-3 = TEEL-3 = Rat oral LD50 (215 mg/kg)
This review generated PAC-1 and PAC-2 values consistent with Rev. 29A and a PAC-3 value inconsistent with Rev. 29A. The Rev. 29A and current TEEL-3 are both based on rat oral LD50 data; however, the current basis is a more conservative dose. The Rev. 29A and current TEEL-2 and TEEL-1 values, sources, and methodologies are consistent.
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/Cyanophos.
LOC: Appendix C (page C-3); https://www.epa.gov/sites/default/files/2015-09/documents/technical_guidance_for_hazard_analysis.pdf
Rat oral LD50: Agricultural and Biological Chemistry., 26(257), 1962. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Cyanophos.
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