PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cyclopentanone | 120-92-3 | 2245 |
16.02
14.01
4.10
11.00
7.01
8.00
7.00
|
|||||||||
| Formula | Synonyms | |||||||||||
| C3H8O | CYCLOPENTANONE, ADIPIC KETONE, ADIPIN KETON, CICLOPENTANONA (DOT SPANISH), CYCLOPENTANONE (DOT FRENCH), DUMASIN, KETOCYCLOPENTANE, KETOPENTAMETHYLENE | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 84.12 | L | 130.6 | 11.4 | 25 | 0.95 @ 20°C |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 6.4 | 70 | 420 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 1.9 | 20 | 120 |
Technical Basis
A review of available sources identified exposure limits and acute toxicity data (LC50, LD50, LDLo) for several species and routes. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The LC50 was evaluated, but it was determined to be an estimate (Section 3.3.1). Analysts selected a mouse intraperitoneal LD50 as the TEEL-3 basis. TEEL-2 and TEEL-1 values were derived according to Table 3.5.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = Mouse intraperitoneal LD50 (1950 mg/kg)
This review generated PAC values inconsistent with Rev. 29A. The Rev. 29A TEEL-3 basis was mouse oral LD50 was not found during the review; instead, analysts selected an available mouse intraperitoneal LD50. The Rev. 29A and current TEEL-2/TEEL-1 use the same methodology, with differences due to the change in TEEL-3.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = Mouse intraperitoneal LD50 (1950 mg/kg)
This review generated PAC values inconsistent with Rev. 29A. The Rev. 29A TEEL-3 basis was mouse oral LD50 was not found during the review; instead, analysts selected an available mouse intraperitoneal LD50. The Rev. 29A and current TEEL-2/TEEL-1 use the same methodology, with differences due to the change in TEEL-3.
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/Cyclopentanone.
LD50 mouse: Comptes Rendus Hebdomadaires des Seances, Academie des Sciences., 254(2245), 1962 [PMID:13877423]. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Cyclopentanone