PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Di-2-ethylhexyl adipate | 103-23-1 |
4.01
7.01
4.07
3.09
3.02
3.10
5.00
5.10
3.11
16.01
|
||||||||||
| Formula | Synonyms | |||||||||||
| C22H42O4 | BIS(2-ETHYLHEXYL) ADIPATE, ADIMOLL DO, ADIPIC ACID, BIS (2-ETHYLHEXYL) ESTER, ADIPIC ACID, BIS(2-ETHYLHEXYL) ESTER, ADIPOL 2EH, ADO, ADO (LUBRICATING OIL), BEHA, BISOFLEX DOA, CRODAMOL DOA, DEHA, DI (2-ETHYLHEXYL) ADIPATE, DI(2-ETHYLHEXYL) ADIPATE, DI-(2-ETHYLHEXYL) ADIPATE, DI-2-ETHYLHEXYL ADIPATE, DIACIZER DOA, DIETHYLHEXYL ADIPATE, DIOCTYL ADIPATE, DOA, EFFEMOLL DOA, EFFOMOLL DA, EFFOMOLL DOA, ERGOPLAST ADDO, FLEXOL A 26, FLEXOL PLASTICIZER 10-A, FLEXOL PLASTICIZER A-26, HATCOL 2908, HEXANEDIOIC ACID, BIS(2-ETHYLHEXYL) ESTER, HEXANEDIOIC ACID, DIOCTYL ESTER, JAYFLEX DOA 2, KEMESTER 5652, KODAFLEX DOA, LANKROFLEX DOA, MOLLAN S, MONOPLEX DOA, NCI-C54386, OCTYL ADIPATE, PLASTHALL DOA, PLASTOMOLL DOA, PX-238, REOMOL DOA, RUCOFLEX PLASTICIZER DOA, SANSOCIZER DOA, SICOL 250, STAFLEX DOA, TRUFLEX DOA, UNIFLEX DOA, VESTINOL OA, WICKENOL 158, WITAMOL 320 | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 370.57 | L | -67.8 | 20 | 0.922 | 4000 |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 27 | 300 | 1800 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 1.8 | 20 | 120 |
Technical Basis
Considering the species and route preferability listed in Section 3.3.2, two rat oral lethal doses (50% kill) were found from different sources. One source, from the National Institutes of Health (NIH), is from 1982 and the most recent source (1996) is SAX. As both sources are credible, the latter, more recent dose is chosen for TEEL development.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Estimated from rat oral LD50 (9110 mg/kg)
This review generated less conservative TEEL values compared with those published in Rev. 29A. In Rev. 29A, the less recent NIH 1982 dose was the TEEL-3 basis, while the current recommendation is based on a more recent study.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Estimated from rat oral LD50 (9110 mg/kg)
This review generated less conservative TEEL values compared with those published in Rev. 29A. In Rev. 29A, the less recent NIH 1982 dose was the TEEL-3 basis, while the current recommendation is based on a more recent study.
References
Rat oral LD50, NIH (1982): Carcinogenesis Bioassay of Di(2-Ethylhexyl)Adipate: https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr212.pdf
Rat oral LD50 (9110 mg/kg): Lewis, R.J. Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold, 1996., p. 71;) via National Center for Biotechnology Information (2023). PubChem Annotation Record for , BIS(2-ETHYLHEXYL) ADIPATE, Source: Hazardous Substances Data Bank (HSDB). Retrieved from https://pubchem.ncbi.nlm.nih.gov/source/hsdb/343
https://cameochemicals.noaa.gov/chemical/8580