PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Diallyldimethylammonium chloride | 7398-69-8 |
3.10
3.09
15.01
15.02
|
||||||||||
| Formula | Synonyms | |||||||||||
| C8.H16.N.Cl | ||||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 161.7 | S crystals |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 7.6 | 83 | 500 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 1.1 | 13 | 76 |
Technical Basis
A review of available sources identified several oral LD50 acute toxicity data for various species (rat, mouse, guinea pig). Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. Multiple rat oral LD50 doses (2520 mg/kg, 3000 mg/kg, 3930 mg/kg) were evaluated for the TEEL-3 basis, and the most conservative was selected as the TEEL-3 basis. TEEL-1 and TEEL-2 values were derived according to Table 3.5.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = Rat oral LD50 (2520 mg/kg)
This review generated PAC values consistent with Rev. 29A*.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = Rat oral LD50 (2520 mg/kg)
This review generated PAC values consistent with Rev. 29A*.
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/Diallyldimethylammonium-chloride.
Rat oral LD50 (2520 mg/kg): Easterday, O.D. (1965b) Acute Oral Absorption -Rats, Diallyldimethylammonium Chloride Polymer and Diallyldimethylammonium Chloride Monomer. Hazleton Laboratories, Falls Church, VA. EPA/Office of Pollution Prevention and Toxics; High Production Volume (HPV) Challenge Program's Robust Summaries and Test Plans. Diallyldimethylammonium Chloride. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Diallyldimethylammonium-chloride.
Rat oral LD50 (3930 mg/kg): Sterner, W. (1975) Acute Oral Toxicity in Rats. International Bioresearch Laboratories, Hanover, Germany. EPA/Office of Pollution Prevention and Toxics; High Production Volume (HPV) Challenge Program's Robust Summaries and Test Plans. Diallyldimethylammonium Chloride. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Diallyldimethylammonium-chloride
Rat oral LD50 (3 gm/kg): Gigiena i Sanitariya53(3)(66), 1988. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Diallyldimethylammonium-chloride.