PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dibromomethane; (Methylene dibromide) | 74-95-3 | 2664 |
13.00
11.01
4.08
7.01
7.00
4.06
4.07
7.11
10.00
3.09
|
|||||||||
| Formula | Synonyms | |||||||||||
| CH2Br2 | DIBROMOMETHANE, DIBROMOMETANO (DOT SPANISH), DIBROMOMÉTHANE (DOT FRENCH), METHYLENE BROMIDE, METHYLENE DIBROMIDE | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 173.85 | L | -52.7 | 97 | 44.4 | 25 | 2.497 @ 20°C |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 21 | 230 | 1400 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 3.0 | 32 | 200 |
Technical Basis
A review of available sources identified the following: LC50 and LD50 animal toxicity data. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route based on the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. Inhalation exposures were scaled to 60-minute equivalents using the ten Berge equation (Section 3.3.4). Of the available toxicity data, the rat 2-hr LC50 was selected as the TEEL-3 basis. TEEL-2 and TEEL-1 values were derived according to Table 3.5.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat 2-hr LC50 (40,000 mg/m3)
This review generated TEEL values that are consistent with those in Rev. 29A., despite different reported sources. In Rev. 29A, the TEEL-2 basis cited a rat TDLo, which was not found during current research. Instead, both the TEEL-2 and TEEL-1 were derived from TEEL-3 using adjustment factors in Table 3.5.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat 2-hr LC50 (40,000 mg/m3)
This review generated TEEL values that are consistent with those in Rev. 29A., despite different reported sources. In Rev. 29A, the TEEL-2 basis cited a rat TDLo, which was not found during current research. Instead, both the TEEL-2 and TEEL-1 were derived from TEEL-3 using adjustment factors in Table 3.5.
References
https://cameochemicals.noaa.gov/chemical/3093
Numerous animal toxicity: National Center for Biotechnology Information (2023). PubChem Compound Summary for CID 3024, Dibromomethane. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Dibromomethane.
Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure, Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982, -,83,1982; Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Dibromomethane.