PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dichloromethylphosphine; (Methylphosphonous dichloride) | 676-83-5 | 2845 |
14.01
14.02
11.01
|
|||||||||
| Formula | Synonyms | |||||||||||
| C.H3.Cl2.P | METHYL PHOSPHONOUS DICHLORIDE, DICHLOROMETHYLPHOSPHINE, DICHLORURE MÉTHYLPHOSPHONEUX (DOT FRENCH), DICLORURO METILFOSFÓNICO (DOT SPANISH), METHYLDICHLOROPHOSPHINE, METHYLPHOSPHINIC DICHLORIDE, METHYLPHOSPHINOUS DICHLORIDE, METHYLPHOSPHONOUS DICHLORIDE, METHYLPHOSPHORUS DICHLORIDE, PHOSPHINE, DICHLOROMETHYL- | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 116.9145 | L | 1.3 |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 2.5 | 27 | 160 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.52 | 5.6 | 33 |
Technical Basis
A review of available sources identified the following: non-human acute toxicity data. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. A rat oral LD50 was selected as a TEEL-3 basis. TEEL-2 and TEEL-1 values were derived according to Table 3.5.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat oral LD50 (830 mg/kg)
This review generated TEEL values that are less conservative than Rev 29A. The Rev. 29A basis was an HHR=3, while the current TEEL-3 basis is a test of the reviewed chemical and is therefore more representative of its acute toxicity.
• TEEL-1 = TEEL-2/11
• TEEL-2 = TEEL-3/6
• TEEL-3 = Rat oral LD50 (830 mg/kg)
This review generated TEEL values that are less conservative than Rev 29A. The Rev. 29A basis was an HHR=3, while the current TEEL-3 basis is a test of the reviewed chemical and is therefore more representative of its acute toxicity.
References
Rat oral LD50: (1977, OECD Guideline 401). https://echa.europa.eu/de/registration-dossier/-/registered-dossier/12194/7/3/2