PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dichlorophenoxyacetic acid, 2,4-; (2,4-D) | 94-75-7 | 2765 |
14.01
11.01
15.02
4.08
4.05
7.01
8.00
7.00
11.00
4.09
|
|||||||||
| Formula | Synonyms | |||||||||||
| C8H6Cl2O3 | 2,4-DICHLOROPHENOXYACETIC ACID, (2,4-DICHLOROPHENOXY)ACETIC ACID, 2,4-D, 2,4-D ACID, 2,4-D, SALTS AND ESTERS, 2,4-DICHLOROPHENOXYETHANOIC ACID, 2,4-DICHLORPHENOXYACETIC ACID, 2,4-PA, ACETIC ACID, (2,4-DICHLOROPHENOXY)-, ACIDE DICHLORO-2,4 PHÉNOXYACÉTIQUE (DOT FRENCH), ACIDO 2,4-DICLOROFENOXIACÉTICO (DOT SPANISH), AGROTECT, AMIDOX, AMINOPIELIK 50SL, AMOXONE, AQUA-KLEEN, B-SELEKTONON, BASALCOAT, BH 2,4-D, BRUSH-RHAP, CHIPCO TURF HERBICIDE "D", CHLOROXONE, CROP RIDER, CROTILIN, D 50, DACAMINE, DEBROUSSAILLANT 600, DECAMINE, DED-WEED, DED-WEED LV-69, DEHERBAN, DESORMONE, DICHLOROPHENOXYACETIC ACID, DICLORDON, DICOPUR, DICOTOX, DINOXOL, DMA 6, DMA-4, DORMONE, EMULSAMINE BK, EMULSAMINE E-3, ENT 8,538, ENVERT 171, ENVERT DT, ESTERON, ESTERONE FOUR, FARMCO, FERNIMINE, FOREDEX 75, HEDONAL, HEDONAL (HERBICIDE), IPANER, LAWN-KEEP, MIRACLE, MONOSAN, MONOSAN HERBI, MOTA MASKROS, NETAGRONE, NSC 423, PENNAMINE, PIELIK, RHODIA, SALVO, SDMA, SUPER D WEEDONE, TRANSAMINE, TRINOXOL, U 46, U-5043, VERTON, VERTON 2D, VIDON 638, WEED TOX, WEED-RHAP, WEEDAR, WEEDONE, WEEDTROL | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 221.04 | S | 140.5 | 20 | 1.42 |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 2.0 | 94 | 500 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.22 | 10 | 55 |
Technical Basis
A review of available sources identified exposure limits (IDLH, OEL-STELs and TWAs) and acute toxicity data (LC50, LD50, TDLo) for several/numerous species and routes. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The most preferred source, the 1990 IDLH, was selected as the TEEL-3. The most preferred species and route toxicity data, a dog oral TDLo, was selected as the TEEL-2 basis. The lowest reported OEL-STEL (Denmark, 15-minute) was selected as the TEEL-1.
• PAC-1 = TEEL-1 = OEL-STEL (2 mg/m3)
• PAC-2 = TEEL-2 = Dog oral TDLo (200 mg/kg; toxicity endpoints: nausea or vomiting)
• PAC-3 = TEEL-3 = IDLH (1990)
This review generated PAC-3 and PAC-2 values consistent with Rev. 29A and an inconsistent TEEL-1. The Rev.29A and current TEEL-3 and TEEL-2 sources and methodologies are consistent. The Rev. 29A TEEL-1 basis was a TLV-TWA, while the current TEEL-1 is an OEL-STEL (Table 3.5, see Note).
• PAC-1 = TEEL-1 = OEL-STEL (2 mg/m3)
• PAC-2 = TEEL-2 = Dog oral TDLo (200 mg/kg; toxicity endpoints: nausea or vomiting)
• PAC-3 = TEEL-3 = IDLH (1990)
This review generated PAC-3 and PAC-2 values consistent with Rev. 29A and an inconsistent TEEL-1. The Rev.29A and current TEEL-3 and TEEL-2 sources and methodologies are consistent. The Rev. 29A TEEL-1 basis was a TLV-TWA, while the current TEEL-1 is an OEL-STEL (Table 3.5, see Note).
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/1486
IDLH: https://www.cdc.gov/niosh/idlh/94757.html
Dog TDLo. JTCTDW 38,747,2000. Retrieved from: https://www.cdc.gov/niosh-rtecs/AG682428.html
Exposure limits: https://www.osha.gov/chemicaldata/750
OELs: https://ilv.ifa.dguv.de/limitvalues/19681