PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Diethyl carbonate | 105-58-8 | 2366 |
5.10
14.01
14.02
11.01
4.07
11.00
10.00
2.00
3.11
7.11
|
|||||||||
| Formula | Synonyms | |||||||||||
| C5.H10.O3 | DIETHYL CARBONATE, CARBONATE D^ÉTHYLE (DOT FRENCH), CARBONATO DE DIETILO (DOT SPANISH), CARBONIC ACID, DIETHYL ESTER, CARBONIC ETHER, DIATOL, ETHYL CARBONATE, ETHYL CARBONATE ((ETO)2CO), EUFIN | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 118.15 | L | 126 | 10.8 | 25 | 0.9752 @ 20°C |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 59 | 650 | 3900 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 12 | 130 | 810 |
Technical Basis
A review of available sources identified exposure limits (OEL-STEL, OEL-TWA) and limited rat acute toxicity data (LD50, LDLo). In addition, GHS health hazard codes (H315, H319, H335; Category 2) were evaluated to determine an appropriate magnitude for TEELs; this corresponds to an approximate HHR=2 (PAC-2 = TEEL-2 = 790 mg/m3). Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. The most preferred toxicity route, a rat oral LDLo, was selected as the TEEL-3 basis. Occupation exposure limits (STEL, TWA; Latvia) were evaluated as TEEL-1 but were not selected because the resultant TEELs were several orders of magnitude greater than toxicity based TEELs, which is not supported by the reported GHS hazards. TEEL-2 and TEEL-1 values were derived according to Table 3.5.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = Rat oral LDLo (15 g/kg)
This review generated PAC values consistent with Rev. 29A*.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = TEEL-3/6
• PAC-3 = TEEL-3 = Rat oral LDLo (15 g/kg)
This review generated PAC values consistent with Rev. 29A*.
References
Chemical and GHS information: https://pubchem.ncbi.nlm.nih.gov/compound/Diethyl-Carbonate.
OEL-STEL (207 ppm, 1000 mg/m3), OEL-TWA (145 ppm, 700 mg/m3): https://ilv.ifa.dguv.de/limitvalues/20807
Rat LDLo. FAO Nutrition Meetings Report Series., 53A(52), 1974. Retrieved from: https://pubchem.n/cbi.nlm.nih.gov/compound/Diethyl-Carbonate.