PAC Database - Detailed Chemical Data
Chemical Identity
| Chemical | CAS# | UN# | Health Code Numbers | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Diethyl chlorophosphate | 814-49-3 |
6.00
4.01
4.05
7.01
8.00
7.00
4.07
7.11
4.11
16.01
|
||||||||||
| Formula | Synonyms | |||||||||||
| C4.H10.Cl.O3.P | DIETHYL CHLOROPHOSPHATE, CHLORODIETHOXYPHOSPHINE OXIDE, CHLORODIETHYLPHOSPHATE, CHLOROPHOSPHORIC ACID, DIETHYL ESTER, DIETHOXYPHOSPHOROUS OXYCHLORIDE, DIETHOXYPHOSPHORUS OXYCHLORIDE, DIETHOXYPHOSPHORYL CHLORIDE, DIETHYL CHLOROPHOSPHONATE, DIETHYL PHOSPHOCHLORIDATE, DIETHYL PHOSPHOROCHLORIDATE, DIETHYL PHOSPHOROCHLORIDE, DIETHYLPHOSPHORIC ACID CHLORIDE, ETHYL PHOSPHOROCHLORIDATE, ETHYL PHOSPHOROCHLORIDATE (CL(ETO)2PO), ETHYL PHOSPHOROCHLORIDATE (ETO)2CLPO, O,O-DIETHYL CHLORIDOPHOSPHATE, O,O-DIETHYL CHLOROPHOSPHATE, O,O-DIETHYL CHLOROPHOSPHONATE, O,O-DIETHYL PHOSPHOROCHLORIDATE, O,O-DIETHYLPHOSPHORYL CHLORIDE, PHOSPHORIC ACID CHLORIDE DIETHYL ESTER, PHOSPHORO- CHLORIDIC ACID, DIETHYL ESTER | |||||||||||
Physical Properties
| Mol Wt | State | MP (°C) | BP (°C) | VP (Hg) | VP (°C) | SG | LEL (ppm) |
|---|---|---|---|---|---|---|---|
| 172.56 | L/S | 1.21 @ 20°C |
PAC Values
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.73 | 8.0 | 11 |
| PAC-1 | PAC-2 | PAC-3 |
|---|---|---|
| 0.10 | 1.1 | 1.6 |
Technical Basis
A review of available sources identified a LOC and LD50 toxicity data for various routes and species. Data sources were selected according to the hierarchy listed in Table 3.1. Toxicity data were selected according to type of exposure, species, and route according to the hierarchies stated in Sections 3.3.1, 3.3.2, and evaluated using factors in Tables 3.2, 3.3, and 3.4. Two oral LD50 data (rat, mouse) were evaluated for the TEEL-3 basis, but when considering the high priority LOC as the TEEL-2, the rat oral LD50 data resulted in a TEEL-3 < TEEL-2; therefore, the mouse oral LD50 was selected as the TEEL-3 basis. The LOC was selected as the TEEL-2. TEEL-1 was derived according to Table 3.5.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = LOC (0.008 g/m3)
• PAC-3 = TEEL-3 = Mouse oral LD50 (100 mg/kg)
This review generated PAC values consistent with Rev. 29A.
• PAC-1 = TEEL-1 = TEEL-2/11
• PAC-2 = TEEL-2 = LOC (0.008 g/m3)
• PAC-3 = TEEL-3 = Mouse oral LD50 (100 mg/kg)
This review generated PAC values consistent with Rev. 29A.
References
Chemical information: https://pubchem.ncbi.nlm.nih.gov/compound/Diethyl-chlorophosphate.
LOC: Appendix C (page C-4); https://www.epa.gov/sites/default/files/2015-09/documents/technical_guidance_for_hazard_analysis.pdf
Mouse oral LD50: National Technical Information Service., OTS0570912. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Diethyl-chlorophosphate.
Rat oral LD50 (11 mg/kg): American Industrial Hygiene Association Journal., 23(95), 1962 [PMID:13914538]. Retrieved from: https://pubchem.ncbi.nlm.nih.gov/compound/Diethyl-chlorophosphate.